| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 13/02/21 22:30 | Unión La Calera | Curico Unido | 2-3 |
| 13/02/21 22:30 | Universidad de Chili | CD Antofagasta | 3-1 |
| 14/02/21 14:30 | Universidad de Concepcion | Universidad Católica | 1-2 |
| 14/02/21 14:30 | Everton | Huachipato | 1-0 |
| 14/02/21 22:00 | Iquique | Santiago Wanderers | 2-0 |
| 14/02/21 22:00 | Deportes La Serena | Audax Italiano | 0-2 |
| 14/02/21 22:00 | Palestino | Coquimbo Unido | 2-2 |
| 14/02/21 22:00 | O'Higgins | Colo-Colo | 1-1 |
| 15/02/21 14:30 | Cobresal | Unión Española | 4-1 |