| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 07/12/25 17:15 | FC Empoli | Palermo FC | 1-3 |
| 07/12/25 19:30 | Sampdoria Genua | Carrarese Calcio 1908 | 3-2 |
| 08/12/25 12:30 | Modena FC | US Catanzaro 1929 | 1-2 |
| 08/12/25 15:00 | US Avellino | FC Venise | 1-1 |
| 08/12/25 15:00 | Frosinone Calcio | Juve Stabia | 3-0 |
| 08/12/25 15:00 | Mantova 1911 | AC Reggiana 1919 | 0-1 |
| 08/12/25 15:00 | Padova Calcio | FC Cesena | 1-1 |
| 08/12/25 15:00 | AC Monza | FC Tirol du Sud | 1-1 |
| 08/12/25 17:15 | SSC Bari | Pescara Calcio | 1-1 |
| 08/12/25 19:30 | Virtus Entella | Spezia Calcio | 0-1 |
| 12/12/25 20:45 | US Lecce | Pisa Sporting Club | 1-0 |
| 13/12/25 15:00 | FC Turin | US Cremonese | 1-0 |
| 13/12/25 18:00 | Parma Calcio 1913 | Lazio Rom | 0-1 |
| 13/12/25 20:45 | Atalanta Bergamo | Cagliari Calcio | 1-0 |
| 14/12/25 12:30 | AC Milan | Sassuolo Calcio | --- |
| 14/12/25 15:00 | AC Florenz | Hellas Verona | --- |
| 14/12/25 15:00 | Udinese Calcio | SSC Naples | --- |
| 14/12/25 18:00 | Genua CFC | Inter Milan | --- |
| 14/12/25 20:45 | FC Bologna | Juventus Turin | --- |
| 15/12/25 20:45 | AS Rome | Como Calcio | --- |