Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 26/02/22 15:00 | 26/02/22 15:00 | Paris FC | FC Sochaux-Montbéliard | 3-1 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | Stade Malherbe Caen | SC Bastia | 2-1 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | AC Ajaccio | Rodez Aveyron | 2-1 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | Amiens SC | Nîmes Olympique | 3-0 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | AJ Auxerre | US Quevilly Rouen | 1-0 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | USL Dunkerque | Dijon FCO | 2-1 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | En Avant Guingamp | Chamois Niortais FC | 1-0 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | Havre AC | AS Nancy-Lorraine | 1-0 | 5 - 7 points |
| 26/02/22 19:00 | 26/02/22 19:00 | Valenciennes FC | Pau FC | 1-0 | 5 - 7 points |
| 28/02/22 20:45 | 28/02/22 20:45 | Grenoble Foot | Toulouse FC | 0-2 | 5 - 7 points |