Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 12/02/22 15:00 | 12/02/22 15:00 | Valenciennes FC | Toulouse FC | 1-3 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | Stade Malherbe Caen | Nîmes Olympique | 4-0 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | Dijon FCO | Pau FC | 0-1 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | USL Dunkerque | Rodez Aveyron | 2-0 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | Grenoble Foot | FC Sochaux-Montbéliard | 1-3 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | Paris FC | US Quevilly Rouen | 3-0 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | AC Ajaccio | En Avant Guingamp | 0-1 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | Amiens SC | Chamois Niortais FC | 3-1 | 5 - 7 points |
| 12/02/22 19:00 | 12/02/22 19:00 | AJ Auxerre | AS Nancy-Lorraine | 1-1 | 5 - 7 points |
| 14/02/22 20:45 | 14/02/22 20:45 | Havre AC | SC Bastia | 2-4 | 5 - 7 points |