Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 26/11/21 20:30 | 26/11/21 20:29 | VfB Stuttgart | FSV Mayence 05 | 2-1 | 2 - 5 points |
| 27/11/21 15:30 | 26/11/21 20:29 | 1. FC Cologne | Bor. Mönchengladbach | 4-1 | 2 - 5 points |
| 27/11/21 15:30 | 26/11/21 20:29 | Hertha BSC | FC Augsburg | 1-1 | 2 - 5 points |
| 27/11/21 15:30 | 26/11/21 20:29 | VfL Wolfsburg | Borussia Dortmund | 1-3 | 2 - 5 points |
| 27/11/21 15:30 | 26/11/21 20:29 | SpVgg Greuther Fürth | 1899 Hoffenheim | 3-6 | 2 - 5 points |
| 27/11/21 15:30 | 26/11/21 20:29 | VfL Bochum | SC Freiburg | 2-1 | 2 - 5 points |
| 27/11/21 18:30 | 26/11/21 20:29 | Bayern Munich | Arminia Bielefeld | 1-0 | 2 - 5 points |
| 28/11/21 15:30 | 26/11/21 20:29 | Eintracht Frankfurt | 1. FC Union Berlin | 2-1 | 2 - 5 points |
| 28/11/21 17:30 | 26/11/21 20:29 | RB Leipzig | Bayer 04 Leverkusen | 1-3 | 2 - 5 points |