Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 21/01/22 20:45 | 21/01/22 20:45 | KV Oostende | Royal Antwerp FC | 1-2 | 5 - 7 points |
| 22/01/22 16:15 | 22/01/22 16:15 | KV Kortrijk | KAS Eupen | 1-1 | 5 - 7 points |
| 22/01/22 18:30 | 22/01/22 18:30 | Sint-Truidense VV | RFC Seraing | 3-1 | 5 - 7 points |
| 22/01/22 18:30 | 22/01/22 18:30 | K. Beerschot V.A. | OH Leuven | 3-1 | 5 - 7 points |
| 22/01/22 20:45 | 22/01/22 20:45 | Sporting Charleroi | La Gantoise | 0-0 | 5 - 7 points |
| 23/01/22 13:30 | 23/01/22 13:30 | Standard Liège | FC Bruges | 2-2 | 5 - 7 points |
| 23/01/22 16:00 | 23/01/22 16:00 | Royale Union Saint-Gilloise | KRC Genk | 2-1 | 5 - 7 points |
| 23/01/22 18:30 | 23/01/22 18:30 | FC Malinois | RSC Anderlecht | 0-1 | 5 - 7 points |
| 23/01/22 21:00 | 23/01/22 21:00 | KSV Cercle Brügge | SV Zulte-Waregem | 3-1 | 5 - 7 points |