Calendrier
| Compétition | Date | Clôture des pronostics | À domicile | A l'extérieur | Groupe | Résultat | Règle des points |
|---|---|---|---|---|---|---|---|
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Brentford FC | Oldham Athletic | - | 7-0 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Preston North End | Cheltenham Town | - | 4-1 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Wigan Athletic | Sunderland AFC | - | 0-2 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Watford FC | Stoke City | - | 1-3 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Norwich City | Liverpool FC | - | 0-3 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Queens Park Rangers | Everton FC | a.TAB | 10-9 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Fulham FC | Leeds United | a.TAB | 5-6 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Manchester City | Wycombe Wanderers | - | 6-1 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Burnley FC | Rochdale AFC | - | 4-1 | 2 - 4 points |
| Liga | 21/09/21 20:45 | 21/09/21 20:45 | Sheffield United | Southampton FC | a.TAB | 4-6 | 2 - 4 points |
| Liga | 22/09/21 20:30 | 22/09/21 20:30 | Brighton Hove Albion | Swansea City | - | 2-0 | 2 - 4 points |
| Liga | 22/09/21 20:45 | 22/09/21 20:45 | Chelsea FC | Aston Villa | a.TAB | 5-4 | 2 - 4 points |
| Liga | 22/09/21 20:45 | 22/09/21 20:45 | Manchester United | West Ham United | - | 0-1 | 2 - 4 points |
| Liga | 22/09/21 20:45 | 22/09/21 20:45 | Millwall FC | Leicester City | - | 0-2 | 2 - 4 points |
| Liga | 22/09/21 20:45 | 22/09/21 20:45 | Arsenal FC | AFC Wimbledon | - | 3-0 | 2 - 4 points |
| Liga | 22/09/21 20:45 | 22/09/21 20:45 | Wolverhampton Wanderers | Tottenham Hotspurs | a.TAB | 4-5 | 2 - 4 points |