Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 17/09/21 21:00 | 17/09/21 21:00 | Racing Club Strasbourg | FC Metz | 3-0 | 2 - 4 points |
| 18/09/21 17:00 | 18/09/21 17:00 | RC Lens | LOSC Lille | 1-0 | 2 - 4 points |
| 18/09/21 21:00 | 18/09/21 21:00 | AS St. Etienne | Girondins de Bordeaux | 1-2 | 2 - 4 points |
| 19/09/21 13:00 | 19/09/21 13:00 | OGC Nice | AS Monaco | 2-2 | 2 - 4 points |
| 19/09/21 15:00 | 19/09/21 15:00 | Stade de Reims | FC Lorient | 0-0 | 2 - 4 points |
| 19/09/21 15:00 | 19/09/21 15:00 | ES Troyes AC | Montpellier Hérault SC | 1-1 | 2 - 4 points |
| 19/09/21 15:00 | 19/09/21 15:00 | Angers SCO | FC Nantes | 1-4 | 2 - 4 points |
| 19/09/21 15:00 | 19/09/21 15:00 | Clermont Foot | Stade Brestois 29 | 1-1 | 2 - 4 points |
| 19/09/21 17:05 | 19/09/21 17:05 | Olympique de Marseille | Stade Rennais FC | 2-0 | 2 - 4 points |
| 19/09/21 20:45 | 19/09/21 20:45 | Paris Saint-Germain | Olympique Lyonnais | 2-1 | 2 - 4 points |