Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 10/09/21 21:00 | 10/09/21 21:00 | FC Lorient | LOSC Lille | 2-1 | 2 - 4 points |
| 11/09/21 17:00 | 11/09/21 17:00 | Paris Saint-Germain | Clermont Foot | 4-0 | 2 - 4 points |
| 11/09/21 21:00 | 11/09/21 21:00 | AS Monaco | Olympique de Marseille | 0-2 | 2 - 4 points |
| 12/09/21 13:00 | 12/09/21 13:00 | Montpellier Hérault SC | AS St. Etienne | 2-0 | 2 - 4 points |
| 12/09/21 15:00 | 12/09/21 15:00 | Girondins de Bordeaux | RC Lens | 2-3 | 2 - 4 points |
| 12/09/21 15:00 | 12/09/21 15:00 | Stade Brestois 29 | Angers SCO | 1-1 | 2 - 4 points |
| 12/09/21 15:00 | 12/09/21 15:00 | FC Metz | ES Troyes AC | 0-2 | 2 - 4 points |
| 12/09/21 15:00 | 12/09/21 15:00 | Stade Rennais FC | Stade de Reims | 0-2 | 2 - 4 points |
| 12/09/21 17:05 | 12/09/21 17:05 | FC Nantes | OGC Nice | 0-2 | 2 - 4 points |
| 12/09/21 20:45 | 12/09/21 20:45 | Olympique Lyonnais | Racing Club Strasbourg | 3-1 | 2 - 4 points |