Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 04/12/21 17:00 | 04/12/21 17:00 | Olympique de Marseille | Stade Brestois 29 | 1-2 | 2 - 4 points |
| 04/12/21 19:00 | 04/12/21 19:00 | LOSC Lille | ES Troyes AC | 2-1 | 2 - 4 points |
| 04/12/21 21:00 | 04/12/21 21:00 | RC Lens | Paris Saint-Germain | 1-1 | 2 - 4 points |
| 05/12/21 13:00 | 05/12/21 13:00 | AS St. Etienne | Stade Rennais FC | 0-5 | 2 - 4 points |
| 05/12/21 15:00 | 05/12/21 15:00 | Montpellier Hérault SC | Clermont Foot | 1-0 | 2 - 4 points |
| 05/12/21 15:00 | 05/12/21 15:00 | Stade de Reims | Angers SCO | 1-2 | 2 - 4 points |
| 05/12/21 15:00 | 05/12/21 15:00 | FC Lorient | FC Nantes | 0-1 | 2 - 4 points |
| 05/12/21 15:00 | 05/12/21 15:00 | AS Monaco | FC Metz | 4-0 | 2 - 4 points |
| 05/12/21 17:00 | 05/12/21 17:00 | OGC Nice | Racing Club Strasbourg | 0-3 | 2 - 4 points |
| 05/12/21 20:45 | 05/12/21 20:45 | Girondins de Bordeaux | Olympique Lyonnais | 2-2 | 2 - 4 points |