Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 09/03/22 18:45 | 09/03/22 18:45 | FC Porto | Olympique Lyonnais | 0-1 | 2 - 4 points |
| 09/03/22 18:45 | 09/03/22 18:45 | Bétis Séville | Eintracht Frankfurt | 1-2 | 2 - 4 points |
| 10/03/22 18:45 | 10/03/22 18:45 | FC Séville | West Ham United | 1-0 | 2 - 4 points |
| 10/03/22 21:00 | 10/03/22 21:00 | FC Barcelone | Galatasaray Istanbul | 0-0 | 2 - 4 points |
| 10/03/22 21:00 | 10/03/22 21:00 | Sporting Braga | AS Monaco | 2-0 | 2 - 4 points |
| 10/03/22 21:00 | 10/03/22 21:00 | Glasgow Rangers | Etoile Rouge Belgrade | 3-0 | 2 - 4 points |
| 10/03/22 21:00 | 10/03/22 21:00 | Atalanta Bergamo | Bayer 04 Leverkusen | 3-2 | 2 - 4 points |