| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 16/12/22 02:15 | Seattle Seahawks | San Francisco 49ers | 13-21 |
| 17/12/22 19:00 | Minnesota Vikings | Indianapolis Colts | 39-36OT |
| 17/12/22 22:30 | Cleveland Browns | Baltimore Ravens | 13-3 |
| 18/12/22 02:15 | Buffalo Bills | Miami Dolphins | 32-29 |
| 18/12/22 19:00 | Jacksonville Jaguars | Dallas Cowboys | 40-34OT |
| 18/12/22 19:00 | New York Jets | Detroit Lions | 17-20 |
| 18/12/22 19:00 | Chicago Bears | Philadelphia Eagles | 20-25 |
| 18/12/22 19:00 | Houston Texans | Kansas City Chiefs | 24-30OT |
| 18/12/22 19:00 | Carolina Panthers | Pittsburgh Steelers | 16-24 |
| 18/12/22 19:00 | New Orleans Saints | Atlanta Falcons | 21-18 |
| 18/12/22 22:05 | Denver Broncos | Arizona Cardinals | 24-15 |
| 18/12/22 22:05 | Las Vegas Raiders | New England Patriots | 30-24 |
| 18/12/22 22:25 | Tampa Bay Buccaneers | Cincinnati Bengals | 23-34 |
| 18/12/22 22:25 | Los Angeles Chargers | Tennessee Titans | 17-14 |
| 19/12/22 02:20 | Washington Commanders | New York Giants | 12-20 |
| 20/12/22 02:15 | Green Bay Packers | Los Angeles Rams | 24-12 |