| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 02/12/22 02:15 | New England Patriots | Buffalo Bills | 10-24 |
| 04/12/22 19:00 | Chicago Bears | Green Bay Packers | 19-28 |
| 04/12/22 19:00 | Houston Texans | Cleveland Browns | 14-27 |
| 04/12/22 19:00 | Baltimore Ravens | Denver Broncos | 10-9 |
| 04/12/22 19:00 | Detroit Lions | Jacksonville Jaguars | 40-14 |
| 04/12/22 19:00 | Atlanta Falcons | Pittsburgh Steelers | 16-19 |
| 04/12/22 19:00 | New York Giants | Washington Commanders | 20-20OT |
| 04/12/22 19:00 | Philadelphia Eagles | Tennessee Titans | 35-10 |
| 04/12/22 19:00 | Minnesota Vikings | New York Jets | 27-22 |
| 04/12/22 22:05 | Los Angeles Rams | Seattle Seahawks | 23-27 |
| 04/12/22 22:05 | San Francisco 49ers | Miami Dolphins | 33-17 |
| 04/12/22 22:25 | Cincinnati Bengals | Kansas City Chiefs | 27-24 |
| 04/12/22 22:25 | Las Vegas Raiders | Los Angeles Chargers | 27-20 |
| 05/12/22 02:20 | Dallas Cowboys | Indianapolis Colts | 54-19 |
| 06/12/22 02:15 | Tampa Bay Buccaneers | New Orleans Saints | 17-16 |