| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 04/04/26 19:00 | Toronto FC | Colorado Rapids | 3-2 |
| 04/04/26 22:30 | New England Revolution | CF Montreal | 3-0 |
| 04/04/26 22:30 | Real Salt Lake | Sporting Kansas City | 3-1 |
| 05/04/26 01:30 | Charlotte FC | Philadelphia Union | 2-1 |
| 05/04/26 01:30 | New York City FC | St. Louis City SC | 1-1 |
| 05/04/26 01:30 | Atlanta United FC | Columbus Crew | 1-3 |
| 05/04/26 01:30 | D.C. United | FC Dallas | 0-4 |
| 05/04/26 01:30 | New York Red Bulls | Cincinnati FC | 4-2 |
| 05/04/26 02:00 | Inter Miami CF | Austin FC | 2-2 |
| 05/04/26 02:30 | Houston Dynamo | Seattle Sounders | 0-1 |
| 05/04/26 02:30 | Chicago Fire | Nashville SC | 1-0 |
| 05/04/26 03:30 | Los Angeles FC | Orlando City | 6-0 |
| 05/04/26 04:30 | San Jose Earthquakes | San Diego FC | 3-0 |
| 05/04/26 04:30 | Vancouver Whitecaps | Portland Timbers | 3-2 |
| 05/04/26 04:30 | Los Angeles Galaxy | Minnesota United FC | 1-2 |