| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 21/03/26 18:00 | Toronto FC | Columbus Crew | 2-1 |
| 21/03/26 21:30 | Philadelphia Union | Chicago Fire | 1-2 |
| 21/03/26 23:15 | Nashville SC | Orlando City | 5-0 |
| 22/03/26 00:30 | Charlotte FC | New York Red Bulls | 6-1 |
| 22/03/26 00:30 | Atlanta United FC | D.C. United | 0-0 |
| 22/03/26 01:30 | St. Louis City SC | New England Revolution | 3-1 |
| 22/03/26 01:30 | Sporting Kansas City | Colorado Rapids | 1-4 |
| 22/03/26 01:30 | FC Dallas | Houston Dynamo | 4-3 |
| 22/03/26 01:45 | Austin FC | Los Angeles FC | 0-0 |
| 22/03/26 03:30 | Vancouver Whitecaps | San Jose Earthquakes | 0-1 |
| 22/03/26 18:00 | New York City FC | Inter Miami CF | 2-3 |
| 22/03/26 18:00 | Cincinnati FC | CF Montreal | 4-3 |
| 22/03/26 19:30 | Minnesota United FC | Seattle Sounders | 0-0 |
| 22/03/26 21:45 | Portland Timbers | Los Angeles Galaxy | 1-1 |
| 23/03/26 00:00 | San Diego FC | Real Salt Lake | 2-2 |