| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 22/01/26 18:45 | Viktoria Plzen | FC Porto | 1-1 |
| 22/01/26 18:45 | Young Boys Bern | Olympique Lyonnais | 0-1 |
| 22/01/26 18:45 | Feyenoord Rotterdam | SK Sturm Graz | 3-0 |
| 22/01/26 18:45 | SC Freiburg | Maccabi Tel Aviv | 1-0 |
| 22/01/26 18:45 | PAOK Saloniki | Bétis Séville | 2-0 |
| 22/01/26 18:45 | FC Bologna | Celtic Glasgow | 2-2 |
| 22/01/26 18:45 | Malmö FF | Etoile Rouge Belgrade | 0-1 |
| 22/01/26 18:45 | Fenerbahce Istanbul | Aston Villa | 0-1 |
| 22/01/26 18:45 | Brann Bergen | FC Midtjylland | 3-3 |
| 22/01/26 21:00 | Ferencvaros Budapest | Panathinaikos Athènes | 1-1 |
| 22/01/26 21:00 | OGC Nice | Go Ahead Eagles Deventer | 3-1 |
| 22/01/26 21:00 | Celta Vigo | LOSC Lille | 2-1 |
| 22/01/26 21:00 | Sporting Braga | Nottingham Forest | 1-0 |
| 22/01/26 21:00 | Red Bull Salzbourg | FC Basel | 3-1 |
| 22/01/26 21:00 | Dinamo Zagreb | FCSB Bukarest | 4-1 |
| 22/01/26 21:00 | Glasgow Rangers | PFC Ludogorets Razgrad | 1-0 |
| 22/01/26 21:00 | AS Rome | VfB Stuttgart | 2-0 |
| 22/01/26 21:50 | FC Utrecht | KRC Genk | 0-2 |