| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 24/09/25 18:45 | PAOK Saloniki | Maccabi Tel Aviv | 0-0 |
| 24/09/25 18:45 | FC Midtjylland | SK Sturm Graz | 2-0 |
| 24/09/25 21:00 | Dinamo Zagreb | Fenerbahce Istanbul | 3-1 |
| 24/09/25 21:00 | Etoile Rouge Belgrade | Celtic Glasgow | 1-1 |
| 24/09/25 21:00 | Sporting Braga | Feyenoord Rotterdam | 1-0 |
| 24/09/25 21:00 | Bétis Séville | Nottingham Forest | 2-2 |
| 24/09/25 21:00 | Malmö FF | PFC Ludogorets Razgrad | 1-2 |
| 24/09/25 21:00 | SC Freiburg | FC Basel | 2-1 |
| 24/09/25 21:00 | OGC Nice | AS Rome | 1-2 |
| 25/09/25 18:45 | LOSC Lille | Brann Bergen | 2-1 |
| 25/09/25 18:45 | Go Ahead Eagles Deventer | FCSB Bukarest | 0-1 |
| 25/09/25 21:00 | Glasgow Rangers | KRC Genk | 0-1 |
| 25/09/25 21:00 | Ferencvaros Budapest | Viktoria Plzen | 1-1 |
| 25/09/25 21:00 | Young Boys Bern | Panathinaikos Athènes | 1-4 |
| 25/09/25 21:00 | Aston Villa | FC Bologna | 1-0 |
| 25/09/25 21:00 | Red Bull Salzbourg | FC Porto | 0-1 |
| 25/09/25 21:00 | FC Utrecht | Olympique Lyonnais | 0-1 |
| 25/09/25 21:00 | VfB Stuttgart | Celta Vigo | 2-1 |