Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 04/12/21 15:00 | 04/12/21 15:00 | AC Milan | US Salernitana | 2-0 | 2 - 5 points |
| 04/12/21 18:00 | 04/12/21 18:00 | AS Rome | Inter Milan | 0-3 | 2 - 5 points |
| 04/12/21 20:45 | 04/12/21 20:45 | SSC Naples | Atalanta Bergamo | 2-3 | 2 - 5 points |
| 05/12/21 12:30 | 05/12/21 12:30 | FC Bologna | AC Florenz | 2-3 | 2 - 5 points |
| 05/12/21 15:00 | 05/12/21 15:00 | Spezia Calcio | Sassuolo Calcio | 2-2 | 2 - 5 points |
| 05/12/21 15:00 | 05/12/21 15:00 | FC Venise | Hellas Verona | 3-4 | 2 - 5 points |
| 05/12/21 18:00 | 05/12/21 18:00 | Sampdoria Genua | Lazio Rom | 1-3 | 2 - 5 points |
| 05/12/21 20:45 | 05/12/21 20:45 | Juventus Turin | FC Genua 1893 | 2-0 | 2 - 5 points |
| 06/12/21 18:30 | 06/12/21 18:30 | FC Empoli | Udinese Calcio | 3-1 | 2 - 5 points |
| 06/12/21 20:45 | 06/12/21 20:45 | Cagliari Calcio | FC Turin | 1-1 | 2 - 5 points |