Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 04/12/21 13:30 | 04/12/21 13:30 | West Ham United | FC Chelsea | 3-2 | 2 - 5 points |
| 04/12/21 16:00 | 04/12/21 16:00 | Newcastle United | FC Burnley | 1-0 | 2 - 5 points |
| 04/12/21 16:00 | 04/12/21 16:00 | FC Southampton | Brighton and Hove Albion | 1-1 | 2 - 5 points |
| 04/12/21 16:00 | 04/12/21 16:00 | Wolverhampton Wanderers | FC Liverpool | 0-1 | 2 - 5 points |
| 04/12/21 18:30 | 04/12/21 18:30 | FC Watford | Manchester City | 1-3 | 2 - 5 points |
| 05/12/21 15:00 | 05/12/21 15:00 | Leeds United | Brentford FC | 2-2 | 2 - 5 points |
| 05/12/21 15:00 | 05/12/21 15:00 | Manchester United | Crystal Palace | 1-0 | 2 - 5 points |
| 05/12/21 15:00 | 05/12/21 15:00 | Tottenham Hotspur | Norwich City | 3-0 | 2 - 5 points |
| 05/12/21 17:30 | 05/12/21 17:30 | Aston Villa | Leicester City | 2-1 | 2 - 5 points |
| 06/12/21 21:00 | 06/12/21 21:00 | FC Everton | FC Arsenal | 2-1 | 2 - 5 points |